Situated near the crossroads of three major interstates (I-75, I-40 and I-81) the airport is located to serve Eastern Tennessee and Western North Carolina.
Service will operate four times weekly on Monday, Tuesday, Thursday and Friday. Flights will depart Knoxville at 7:45 a.m. and arrive at Orlando Sanford at 9:25 a.m. Flights will depart Orlando Sanford at 5:30 p.m. and arrive in Knoxville at 7:10 p.m. (all flight times are local).
Allegiant will use 150-seat, MD-80 series jet aircraft on the route.
Knoxville is one of 22 nonstop destinations for Allegiant from Sanford.